Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MEF2C All Species: 29.09
Human Site: Y157 Identified Species: 53.33
UniProt: Q06413 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q06413 NP_002388.2 473 51221 Y157 S S H N S L V Y S N P V S S L
Chimpanzee Pan troglodytes XP_001139828 503 54271 Y155 T S P N A L S Y T N P G S S L
Rhesus Macaque Macaca mulatta XP_001086412 483 52310 Y175 S S H N S L V Y S N P V S S L
Dog Lupus familis XP_858441 472 51065 Y156 S S H N S L V Y S N P V S S L
Cat Felis silvestris
Mouse Mus musculus Q8CFN5 474 51260 Y157 S S H N S L V Y S N P V S T L
Rat Rattus norvegicus Q2MJT0 495 53235 Y156 T S P N A L S Y T N P G S S L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510456 503 54885 Y187 S N H N S L V Y S N P V S S L
Chicken Gallus gallus Q9W6U8 499 53650 P164 P G S S L V S P S L A A S S S
Frog Xenopus laevis Q03413 498 54053 Q166 P G G S L I T Q S L M T S S L
Zebra Danio Brachydanio rerio NP_571387 465 49956 Y156 S N P N S L I Y G H P G A S L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P40791 539 57097 G157 P V S V P V P G S Y G D N L L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38847 268 30310
Baker's Yeast Sacchar. cerevisiae P38128 452 49396 G144 P L A S N D A G N A G V S T P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 63.4 93.3 99.1 N.A. 98.7 56.5 N.A. 93 63.1 56.6 79.4 N.A. 32.4 N.A. N.A. N.A.
Protein Similarity: 100 74.3 94.8 99.3 N.A. 99.7 69.2 N.A. 94 74.1 70.4 88.5 N.A. 50 N.A. N.A. N.A.
P-Site Identity: 100 60 100 100 N.A. 93.3 60 N.A. 93.3 20 26.6 53.3 N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 80 100 100 N.A. 100 80 N.A. 100 33.3 40 80 N.A. 26.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 23.8 21.5 N.A.
Protein Similarity: N.A. N.A. N.A. 36.7 37.4 N.A.
P-Site Identity: N.A. N.A. N.A. 0 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 0 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 16 0 8 0 0 8 8 8 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 8 0 0 0 0 0 8 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 16 8 0 0 0 0 16 8 0 16 24 0 0 0 % G
% His: 0 0 39 0 0 0 0 0 0 8 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 8 8 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 8 0 0 16 62 0 0 0 16 0 0 0 8 77 % L
% Met: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % M
% Asn: 0 16 0 62 8 0 0 0 8 54 0 0 8 0 0 % N
% Pro: 31 0 24 0 8 0 8 8 0 0 62 0 0 0 8 % P
% Gln: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 47 47 16 24 47 0 24 0 62 0 0 0 77 70 8 % S
% Thr: 16 0 0 0 0 0 8 0 16 0 0 8 0 16 0 % T
% Val: 0 8 0 8 0 16 39 0 0 0 0 47 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 62 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _